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Chemistry of Heterocyclic Compounds

, Volume 52, Issue 8, pp 574–577 | Cite as

3-(Nitromethyl)-3,4-dihydroquinoxalin-2(1H)-ones: synthesis and structure

  • Vasilii V. Pelipko
  • Sergey V. Makarenko
  • Valentina M. BerestovitskayaEmail author
  • Ruslan I. Baichurin
Article

Reactions of ethyl 3-nitroacrylate with o-phenylenediamine and its substituted derivatives were used for the synthesis of 3-(nitromethyl)-3,4-dihydroquinoxalin-2(1H)-ones, followed by structural characterization. These compounds were found to undergo elimination of nitromethane, leading to quinoxalin-2(1H)-ones.

Keywords

1,2-diaminobenzene ethyl 3-nitroacrylate 3-(nitromethyl)-3,4-dihydroquinoxalin-2(1H)-one quinoxalin-2(1H)-one aza-Michael reaction 

Notes

This work received financial support from the Ministry of Education and Science of Russian Federation, within the framework of baseline of the State Assignment.

Supplementary material

10593_2016_1934_MOESM1_ESM.pdf (5.7 mb)
ESM 1 (PDF 5820 kb)

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Vasilii V. Pelipko
    • 1
  • Sergey V. Makarenko
    • 1
  • Valentina M. Berestovitskaya
    • 1
    Email author
  • Ruslan I. Baichurin
    • 1
  1. 1.Herzen State Pedagogical University of RussiaSaint PetersburgRussia

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