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Chemistry of Heterocyclic Compounds

, Volume 52, Issue 8, pp 570–573 | Cite as

New route for the synthesis of N-alkyl-2-(phenylsulfonyl)anilines

  • Aisha HossanEmail author
Article

The main objective of this work was to study the rearrangement reactions of 1-alkyl-2-[(phenylsulfonyl)methyl]pyridinium iodides in the presence of various nucleophiles, leading to N-alkyl-2-(phenylsulfonyl)aniline derivatives. The best results were achieved with alkylammonium sulfites, leading to pyridine ring opening followed by recyclization to give diphenyl sulfone derivatives in up to 78% yields.

Keywords

alkylammonium sulfites diaryl sulfones 2-[(phenylsulfonyl)methyl]pyridine pyridinium salts sodium benzenesulfinate 

Notes

The author is deeply thankful to Dr. Ahmed A. Fadda, Professor of Organic Chemistry, Faculty of Science, Mansoura University, for suggesting the research topic, continuous guidance, practical help, and valuable discussions.

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Department of Chemistry, Faculty of Science for GirlsKing Khalid UniversityAbhaSaudi Arabia

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