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The rearrangement of trifluoroacetylchromenes to trifluoromethylchromenols

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Chemistry of Heterocyclic Compounds Aims and scope

The reaction of o-phenylenediamine with condensed 4H-pyrans containing a trifluoroacetyl group at the β-position relative to the oxygen atom led to 2-(trifluoromethyl)chroman-2-ols and 3-(trifluoromethyl)-2,3-dihydro-1H-benzo[f]chromen-3-ols via a cascade process that was initiated by a Michael reaction.

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The work was performed with financial support from the Ministry of Education and Science of the Russian Federation within the framework of the Project part of the State assignment for scientific activity (4.1597.2014/К) and the Grant Council of the President of the Russian Federation for support of young Russian scientists (grant MD-5833.2016.3).

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Authors and Affiliations

  1. Samara State Technical University, 244 Molodogvardeyskaya St., Samara, 443100, Russia

    Vitaly A. Osyanin, Yulia V. Popova, Darina V. Sakhnenko, Dmitry V. Osipov & Yuri N. Klimochkin

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  1. Vitaly A. Osyanin
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  2. Yulia V. Popova
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  3. Darina V. Sakhnenko
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  4. Dmitry V. Osipov
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  5. Yuri N. Klimochkin
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Correspondence to Vitaly A. Osyanin.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2016, 52(8), 559–563

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Osyanin, V.A., Popova, Y.V., Sakhnenko, D.V. et al. The rearrangement of trifluoroacetylchromenes to trifluoromethylchromenols. Chem Heterocycl Comp 52, 559–563 (2016). https://doi.org/10.1007/s10593-016-1931-6

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  • DOI: https://doi.org/10.1007/s10593-016-1931-6

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