Chemistry of Heterocyclic Compounds

, Volume 52, Issue 8, pp 541–545 | Cite as

Synthesis of Chiral Phosphazene Bases

  • Martins Priede
  • Elina Priede
  • Jaan Saame
  • Ivo Leito
  • Edgars SunaEmail author

Air-stable and crystalline tetraaminophosphonium tetrafluoroborates possessing chiral, enantiomerically pure 1,2-diamine moiety have been synthesized by a three-step sequential one-pot approach. The tetrafluoroborate salts can be purified by recrystallization or chromatography and subsequently converted to the phosphazene bases by treatment with t-BuOK. Basicity values in tetrahydrofuran have been measured for the obtained phosphazene bases by means of spectrophotometric titration.


phosphazene bases tetraaminophosphonium salts basicity one-pot synthesis pKip value 


Authors thank Dr. S. Belyakov (Latvian Institute of Organic Synthesis) for X-ray crystallographic analysis.

Supplementary material

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ESM 1 (PDF 325 kb)


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Martins Priede
    • 1
  • Elina Priede
    • 1
  • Jaan Saame
    • 2
  • Ivo Leito
    • 2
  • Edgars Suna
    • 1
    Email author
  1. 1.Latvian Institute of Organic SynthesisRigaLatvia
  2. 2.Institute of ChemistryUniversity of TartuTartuEstonia

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