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Chemistry of Heterocyclic Compounds

, Volume 52, Issue 6, pp 415–420 | Cite as

Domino reactions of 1-substituted N-(cyanomethyl)isoquinolinium salts with salicylic aldehydes

  • Leonid G. Voskressensky
  • Ekaterina A. Sokolova
  • Aleksey A. Festa
  • Dorateya A. Enina
  • Alexander V. Aksenov
  • Aleksey V. Varlamov
Article
  • 92 Downloads
Transformations of N-cyanomethyl-substituted 1-methyl- and 1-phenylisoquinolinium salts were studied in the presence of various o-hydroxybenzaldehydes, leading to the formation of substituted chromeno[2',3':4,5]imidazo[2,1-a]isoquinolines. 1,8-Diazabicyclo- [5.4.0]undec-7-ene was shown to be a superior base in this reaction compared to sodium carbonate.

Keywords

isoquinoline salicylic aldehyde domino reaction quaternary salts 

Notes

This work was financially supported by the Ministry of Education and Science of Russian Federation within the program " The Project of Improving the Competitiveness of the Leading Russian Universities among the World's Leading Research and Education Centers" in years 2016–2020 and the Russian Foundation for Basic Research (grants 16-53-540004, 16-33-00640mol_a, and U.M.N.I.K. (2325GU1/2014)).

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Leonid G. Voskressensky
    • 1
  • Ekaterina A. Sokolova
    • 1
  • Aleksey A. Festa
    • 1
  • Dorateya A. Enina
    • 1
  • Alexander V. Aksenov
    • 2
  • Aleksey V. Varlamov
    • 1
  1. 1.Peoples’ Friendship University of RussiaMoscowRussia
  2. 2.North-Caucasus Federal UniversityStavropolRussia

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