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Domino reactions of 1-substituted N-(cyanomethyl)isoquinolinium salts with salicylic aldehydes

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Chemistry of Heterocyclic Compounds Aims and scope

Transformations of N-cyanomethyl-substituted 1-methyl- and 1-phenylisoquinolinium salts were studied in the presence of various o-hydroxybenzaldehydes, leading to the formation of substituted chromeno[2',3':4,5]imidazo[2,1-a]isoquinolines. 1,8-Diazabicyclo- [5.4.0]undec-7-ene was shown to be a superior base in this reaction compared to sodium carbonate.

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This work was financially supported by the Ministry of Education and Science of Russian Federation within the program " The Project of Improving the Competitiveness of the Leading Russian Universities among the World's Leading Research and Education Centers" in years 2016–2020 and the Russian Foundation for Basic Research (grants 16-53-540004, 16-33-00640mol_a, and U.M.N.I.K. (2325GU1/2014)).

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Authors and Affiliations

  1. Peoples’ Friendship University of Russia, 6 Miklukho-Maklaya St, Moscow, 117198, Russia

    Leonid G. Voskressensky, Ekaterina A. Sokolova, Aleksey A. Festa, Dorateya A. Enina & Aleksey V. Varlamov

  2. North-Caucasus Federal University, 1 Pushkina St, Stavropol, 350009, Russia

    Alexander V. Aksenov

Authors
  1. Leonid G. Voskressensky
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  2. Ekaterina A. Sokolova
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  3. Aleksey A. Festa
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  4. Dorateya A. Enina
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  5. Alexander V. Aksenov
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  6. Aleksey V. Varlamov
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Corresponding author

Correspondence to Leonid G. Voskressensky.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2016, 52(6), 415–420

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Voskressensky, L.G., Sokolova, E.A., Festa, A.A. et al. Domino reactions of 1-substituted N-(cyanomethyl)isoquinolinium salts with salicylic aldehydes. Chem Heterocycl Comp 52, 415–420 (2016). https://doi.org/10.1007/s10593-016-1903-x

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  • DOI: https://doi.org/10.1007/s10593-016-1903-x

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