Chemistry of Heterocyclic Compounds

, Volume 52, Issue 4, pp 275–278 | Cite as

Functionalized 2'-carboxamidodeoxybenzoins by ring opening of 3-aryl-1H-isochromen-1-ones with secondary amines

  • Olga V. Shablykina
  • Viktoria S. Moskvina
  • Valentina V. Ishchenko
  • Eugenia B. Valter
  • Volodymir P. Khilya

An efficient approach based on pyrone ring opening in 3-arylisocoumarins in the presence of cyclic secondary amines was developed in order to prepare amides of deoxybenzoin-2'-carboxylic acids, diverse functionalized structures useful for the synthesis of polyfunctional compounds.


3-arylisocoumarins 2'-carboxamidodeoxybenzoins N-nucleophiles amidation ring opening 


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Olga V. Shablykina
    • 1
  • Viktoria S. Moskvina
    • 1
  • Valentina V. Ishchenko
    • 1
  • Eugenia B. Valter
    • 1
  • Volodymir P. Khilya
    • 1
  1. 1.Taras Shevchenko National University of KyivKyivUkraine

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