Direct oxidative nucleophilic substitution of hydrogen atom in acridine molecule was used to synthesize 9-acylaminoacridines. The prototropic amine-imine tautomerism of these compounds was studied.
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Here and further the 1H and 13C NMR signals of trifluoroacetic acid are not listed. The atom numbering in phenyl group is indicated with apostrophes.
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This work was performed with financial support from the Ministry of Education and Science of Russian Federation (project 4.141.2014/K).
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A Supplementary information file containing 1H and 13C NMR spectra of the synthesized compounds is available online at http://link.springer.com/journal/10593.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2016, 52(2), 104–109
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Demidov, O.P., Borovlev, I.V., Amangasieva, G.A. et al. Oxidative SNH amidation of acridine and tautomerism of N-(acridin-9-yl)benzamides. Chem Heterocycl Comp 52, 104–109 (2016). https://doi.org/10.1007/s10593-016-1841-7
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DOI: https://doi.org/10.1007/s10593-016-1841-7