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Chemistry of Heterocyclic Compounds

, Volume 51, Issue 10, pp 944–947 | Cite as

Reversible condensation of 4-arylidene-1,2-dimethyl-1H-imidazol-5(4H)-ones with aromatic acyl chlorides

  • Svetlana V. Golodukhina
  • Nadezhda S. Baleeva
  • Konstantin S. Mineyev
  • Mikhail S. BaranovEmail author
Article

(Z)-1,2-Dimethyl-4-(4-methoxybenzylidene)-1H-imidazol-5(4H)-one underwent a condensation reaction with aromatic acyl chlorides, forming keto derivatives that were structurally similar to chromophores of red fluorescent proteins, as well as to the products of their maturation and/or degradation. The reverse reaction of the obtained products was observed upon treatment with aqueous alkali.

Keywords

imidazolones chromophores fluorescent proteins condensation 

Notes

The study was performed with financial support from the Russian Foundation for Basic Research in the framework of the project No. 14-50-00131. The equipment of Collective Use Center of the Institute of Bioorganic Chemistry was used for part of this research.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Svetlana V. Golodukhina
    • 1
  • Nadezhda S. Baleeva
    • 1
    • 2
  • Konstantin S. Mineyev
    • 1
  • Mikhail S. Baranov
    • 1
    • 2
    Email author
  1. 1.Institute of Bioorganic Chemistry named after Academicians M. M. Shemyakin and Yu. A. Ovchinnikov, Russian Academy of SciencesMoscowRussia
  2. 2.Russian National Research Medical University named after N. I. PirogovMoscowRussia

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