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Microwave synthesis of 2-[(E)-2-(1H-indol-3-yl)vinyl]hetarenes

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Chemistry of Heterocyclic Compounds Aims and scope

A new highly efficient method for the condensation of (indol-3-yl)carbaldehydes with 2-methylazoles and 2-methylazines under activation with microwave irradiation is developed. The method provides high yields of structural scaffolds of bishetarylethylene fluorescent sensors that found widespread application in medicinal, bioorganic, and pharmaceutical chemistry.

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Financial support to this program was provided by the Council for Grants of the President of the Russian Federation for Support of Young Russian Scientists with PhD degree (MK-5733.2015.3).

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Authors and Affiliations

  1. North-Caucasus Federal University, 1 Pushkin St., Stavropol, 355009, Russia

    Alexander V. Aksenov, Oleg N. Nadein, Nicolai A. Aksenov, Anton A. Skomorokhov, Inna V. Aksenova & Michael A. Rubin

  2. University of Kansas, 1251 Wescoe Hall Drive, Lawrence, KS, 66045-7582, USA

    Michael A. Rubin

Authors
  1. Alexander V. Aksenov
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  2. Oleg N. Nadein
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  3. Nicolai A. Aksenov
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  4. Anton A. Skomorokhov
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  5. Inna V. Aksenova
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  6. Michael A. Rubin
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Corresponding authors

Correspondence to Alexander V. Aksenov or Michael A. Rubin.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2015, 51(10), 865–869

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Aksenov, A.V., Nadein, O.N., Aksenov, N.A. et al. Microwave synthesis of 2-[(E)-2-(1H-indol-3-yl)vinyl]hetarenes. Chem Heterocycl Comp 51, 865–868 (2015). https://doi.org/10.1007/s10593-015-1788-0

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  • DOI: https://doi.org/10.1007/s10593-015-1788-0

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