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An effective synthesis of (1Н-1,2,4-triazol-3-yl)furoxans

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Chemistry of Heterocyclic Compounds Aims and scope

A general, simple, and effective method has been developed for the preparation of previously practically unknown (5-R-1Н-1,2,4-triazol-3-yl)furoxans with various substituents at the other carbon atom of furoxan ring, based on condensation of furoxanylamidrazones with electrophilic reagents (cyanogen bromide, acetic and trifluoroacetic anhydrides).

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This work was performed with financial support from the Russian Science Fund (grant 14-50-00-126).

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow, 119991, Russia

    Leonid L. Fershtat, Margarita A. Epishina, Igor V. Ovchinnikov, Vadim V. Kachala & Nina N. Makhova

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  1. Leonid L. Fershtat
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  2. Margarita A. Epishina
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  3. Igor V. Ovchinnikov
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  4. Vadim V. Kachala
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  5. Nina N. Makhova
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Correspondence to Nina N. Makhova.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2015, 51(8), 754–759

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Fershtat, L.L., Epishina, M.A., Ovchinnikov, I.V. et al. An effective synthesis of (1Н-1,2,4-triazol-3-yl)furoxans. Chem Heterocycl Comp 51, 754–759 (2015). https://doi.org/10.1007/s10593-015-1771-9

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  • DOI: https://doi.org/10.1007/s10593-015-1771-9

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