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Microwave-Assisted Synthesis of New Quinazolinone and (dihydroquinazolinylphenyl)oxazolone Derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

2,3-Dihydroquinazolin-4(1H)-one derivatives were synthesized via a one-pot, three-component reaction of isatoic anhydride and an aromatic aldehyde with 4-aminohippuric acid, catalyzed by acetic acid. After completion of the reaction, the corresponding products were reacted with an aromatic aldehyde, acetic anhydride, and sodium acetate to yield oxazolone derivatives. The reactions were carried out under microwave irradiation and reflux.

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Authors and Affiliations

  1. Mining Engineering Department, Higher Education Complex of Zarand, Shahid Bahonar University, Kerman, 7761156391, Iran

    Samieh Fozooni

  2. Department of Chemistry, Payame Noor University, Tehran, 19395-4697, Iran

    Halime Firoozi

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  1. Samieh Fozooni
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  2. Halime Firoozi
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Correspondence to Samieh Fozooni.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2015, 51(4), 340–345

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Fozooni, S., Firoozi, H. Microwave-Assisted Synthesis of New Quinazolinone and (dihydroquinazolinylphenyl)oxazolone Derivatives. Chem Heterocycl Comp 51, 340–345 (2015). https://doi.org/10.1007/s10593-015-1705-6

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  • DOI: https://doi.org/10.1007/s10593-015-1705-6

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