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Ultrasound-Mediated Synthesis of 2,4,6-Triaryl-Pyridines Using MgAl2O4 Nanostructures

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Chemistry of Heterocyclic Compounds Aims and scope

Nanocrystalline MgAl2O4 was found to be a highly efficient catalyst for the preparation of 2,4,6-triaryl-pyridines from the reaction of acetophenone derivatives, aryl aldehydes, and ammonium acetate under sonic condition for the first time. The present methodology offers several advantages, such as excellent yields, simple procedure, shorter reaction times, and milder conditions; the catalyst also exhibited remarkable reusable activity. This procedure is much simpler and faster than the protocols published to date.

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We gratefully acknowledge financial support from the Research Council of the University of Kashan, grant No. 256722/28.

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Authors and Affiliations

  1. Laboratory of Organic Chemistry Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P. O. Box, 87317-51167, Kashan, I. R. Iran

    Z. Zarnegar, J. Safari & M. Borjian-borujeni

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  1. Z. Zarnegar
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  2. J. Safari
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  3. M. Borjian-borujeni
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Correspondence to J. Safari.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1832-1840, December, 2014.

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Zarnegar, Z., Safari, J. & Borjian-borujeni, M. Ultrasound-Mediated Synthesis of 2,4,6-Triaryl-Pyridines Using MgAl2O4 Nanostructures. Chem Heterocycl Comp 50, 1683–1691 (2015). https://doi.org/10.1007/s10593-015-1638-0

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  • DOI: https://doi.org/10.1007/s10593-015-1638-0

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