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An Effective Activation of Palladium Phosphine Complexes in Aqueous Phase Reactions of Hetero-Aromatic Boronic Acids with Aryl Halides

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Chemistry of Heterocyclic Compounds Aims and scope

We have developed a simple and effective method for the activation of palladium phosphine complexes in the Suzuki reaction (TON up to 9800, TOF up to 58800 h-1) by selecting an aqueous reaction medium instead of organic solvents. This method was elaborated for a high yield synthesis of heteroaromatic biaryls with furyl and thienyl groups.

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Authors and Affiliations

  1. Moscow M. V. Lomonosov State University, 1, Build. 3 Leninskie Gory, Moscow, 119991, Russia

    N. A. Bumagin, I. S. Veselov & D. S. Belov

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  1. N. A. Bumagin
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  2. I. S. Veselov
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  3. D. S. Belov
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Correspondence to N. A. Bumagin.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 24-31, 2014.

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Bumagin, N.A., Veselov, I.S. & Belov, D.S. An Effective Activation of Palladium Phosphine Complexes in Aqueous Phase Reactions of Hetero-Aromatic Boronic Acids with Aryl Halides. Chem Heterocycl Comp 50, 19–25 (2014). https://doi.org/10.1007/s10593-014-1443-1

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