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Synthesis of 2-Arylaminopyrimidines from 1,4,6-Trisubstituted Pyrimidine-2(1H)-Thiones*

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Chemistry of Heterocyclic Compounds Aims and scope

A method for the synthesis of 2-anilino-substituted pyrimidines via Dimroth-type ring transformation of 1,4,6-trisubstituted pyrimidine-2(1H)-thiones has been developed.

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This work was supported by the European Regional Development Fund (ERDF) project No. 2DP/2.1.1.1.0/10/APIA/VIAA/065.

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Authors and Affiliations

  1. Latvian Institute of Organic Synthesis, 21 Aizkraukles St., Riga, LV-1006, Latvia

    D. Muceniece, O. Kodolins & V. Lusis

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  1. D. Muceniece
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  2. O. Kodolins
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  3. V. Lusis
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Correspondence to V. Lusis.

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*Dedicated to Prof. Jānis Stradiņš on the occasion of his 80th birthday.

Published in Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1788-1796, November, 2013.

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Muceniece, D., Kodolins, O. & Lusis, V. Synthesis of 2-Arylaminopyrimidines from 1,4,6-Trisubstituted Pyrimidine-2(1H)-Thiones*. Chem Heterocycl Comp 49, 1658–1666 (2014). https://doi.org/10.1007/s10593-014-1417-3

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  • DOI: https://doi.org/10.1007/s10593-014-1417-3

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