Chemistry of Heterocyclic Compounds

, Volume 49, Issue 11, pp 1599–1610 | Cite as

The Reactivity Trends in Electrochemical Chlorination and Bromination of N-Substituted and N-Unsubstituted Pyrazoles*

  • B. V. LyalinEmail author
  • V. A. Petrosyan

Our investigation of electrochemical chlorination and bromination of pyrazoles decorated with electron-withdrawing and electron-donating groups showed that the product yield and composition depended on the substitution at the N-1 atom. We have shown for the first time the significant differences in halogenation reactivity patterns of N-unsubstituted and N-alkylpyrazoles.


N-alkylpyrazole pyrazole electrochemical bromination electrochemical chlorination 


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© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussia

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