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Isoxazol-3-yl(Isothiazol-3-yl)-1,2,4-Triazoles, Tetrazoles, and -1,3,4-Oxadiazoles: Synthesis, Palladium Complexes, and Catalytic Applications

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Chemistry of Heterocyclic Compounds Aims and scope

We used 5-arylisoxazole-3-carbonitriles and 4-R-5-chloroisothiazole-3-carbonitriles to prepare the corresponding (5-arylisoxazol-3-yl)- and (4-R-5-chloroisothiazol-3-yl)-1,2,4-triazoles, -tetrazoles, and -1,3,4-oxadiazoles. The obtained bis-heterocycles along with some of the intermediate monocyclic azoles formed palladium complexes that were highly active Suzuki reaction catalysts in aqueous and aqueous-alcohol media.

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This work was carried out with financial support from the Russian Foundation for Basic Research (grants 12-08-90025-Bel_а, 11-08-00353-а) and the Belarusian Republican Foundation for Fundamental Research (grant H12R-024).

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Authors and Affiliations

  1. Moscow M. V. Lomonosov State University, 1, Build. 3, Leninskie Gory, Moscow, 119991, Russia

    N. A. Bumagin, M. V. Livantsov & N. E. Golantsov

  2. Institute of Physical-Organic chemistry, National Academy of Sciences of Belarus, 13 Surganova St., Minsk, 220072, Belarus

    S. K. Petkevich, A. V. Kletskov & V. I. Potkin

Authors
  1. N. A. Bumagin
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  2. S. K. Petkevich
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  3. A. V. Kletskov
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  4. M. V. Livantsov
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  5. N. E. Golantsov
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  6. V. I. Potkin
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Correspondence to N. A. Bumagin.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1633-1649, October, 2013.

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Bumagin, N.A., Petkevich, S.K., Kletskov, A.V. et al. Isoxazol-3-yl(Isothiazol-3-yl)-1,2,4-Triazoles, Tetrazoles, and -1,3,4-Oxadiazoles: Synthesis, Palladium Complexes, and Catalytic Applications. Chem Heterocycl Comp 49, 1515–1529 (2014). https://doi.org/10.1007/s10593-014-1403-9

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