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A simple and efficient approach to the synthesis of furopyran derivatives: four-component reaction of isocyanides with arylidene-substituted Meldrum’s acid

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Chemistry of Heterocyclic Compounds Aims and scope

A four-component (3+1) reaction of an alkyl isocyanide with arylidene-substituted Meldrum’s acid in CH2Cl2 at room temperature produced furo[3,4-b]pyran-5(7H)-one derivatives in good yields. The structures of the synthesized compounds were confirmed by IR, NMR spectroscopy, mass spectra, and elemental analysis.

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Authors and Affiliations

  1. Kharazmi (Tarbiat Moallem) Uinversity, 43 Mofateh Ave., Tehran, 15719-14911, Iran

    A. Habibi & N. Taghipoor

  2. Young Researchers and Elites Club, Kerman Branch, Islamic Azad University, Kerman, Iran

    E. Sheikhhosseini

Authors
  1. A. Habibi
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  2. E. Sheikhhosseini
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  3. N. Taghipoor
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Correspondence to A. Habibi.

Additional information

Published in Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1040-1045, July, 2013.

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Habibi, A., Sheikhhosseini, E. & Taghipoor, N. A simple and efficient approach to the synthesis of furopyran derivatives: four-component reaction of isocyanides with arylidene-substituted Meldrum’s acid. Chem Heterocycl Comp 49, 968–973 (2013). https://doi.org/10.1007/s10593-013-1333-y

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  • DOI: https://doi.org/10.1007/s10593-013-1333-y

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