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Cyclocondensation of 3(5)-Aminopyrazoles with Arylglyoxals and Cyclohexane-1,3-diones

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Chemistry of Heterocyclic Compounds Aims and scope

Partly hydrogenated 4-aroyl-substituted pyrazolo[3,4-b]quinolin-5-ones and 5-aroyl-substituted pyrazolo[1,5-a]quinazolin-6-ones were obtained by three-component cyclocondensation of substituted 3(5)-aminopyrazoles with the arylglyoxal hydrates and dimedone, 1,3-cyclohexanedione, or 4,4-dimethylcyclohexanedione in an alcohol medium. The chemical transformations of pyrazolo[3,4-b]quinolin5-ones in reactions with hydrazine hydrate and also upon alkylation, acylation, and oxidation were studied.

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Authors and Affiliations

  1. State Scientific Institution “Institute for Single Crystals of National Academy of Sciences of Ukraine, 60 Lenina Ave., Kharkiv, 61001, Ukraine

    O. N. Petrova, L. L. Zamigailo, M. G. Shirobokova, S. V. Shishkina, O. V. Shishkin, V. I. Musatov & V. V. Lipson

  2. V. N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv, 61022, Ukraine

    O. V. Shishkin & V. V. Lipson

  3. State Institution “V. Ya. Danilevsky Institute for Endocrine Pathology Problems of the Academy of Medical Sciences of Ukraine”, 10 Artema St., Kharkiv, 61002, Ukraine

    V. V. Lipson

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  1. O. N. Petrova
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  2. L. L. Zamigailo
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  3. M. G. Shirobokova
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  4. S. V. Shishkina
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  5. O. V. Shishkin
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  6. V. I. Musatov
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  7. V. V. Lipson
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Correspondence to V. V. Lipson.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1026–1039, July, 2013.

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Petrova, O.N., Zamigailo, L.L., Shirobokova, M.G. et al. Cyclocondensation of 3(5)-Aminopyrazoles with Arylglyoxals and Cyclohexane-1,3-diones. Chem Heterocycl Comp 49, 955–967 (2013). https://doi.org/10.1007/s10593-013-1332-z

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  • DOI: https://doi.org/10.1007/s10593-013-1332-z

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