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Study of plant coumarins. 12*. Synthesis of 2-(1,2,3-triazolyl)-modified furocoumarins

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Chemistry of Heterocyclic Compounds Aims and scope

Bromooreoselone reacted with sodium azide to give 2-azidooreoselone, which was highly reactive in a catalytic Huisgen reaction with various terminal alkynes. These reactions yielded 4-substituted 2-(triazol-1-yl)furocoumarins. The reaction of oreoselone azide with dimethyl acetylene-1,2-di-carboxylate gave 2-[(4,5-dimethoxycarbonyl)triazolyl]oreoselone and reaction with 7-ethynyl-6-methoxycarbonylcoumarin gave 1,4-dicoumarin-substituted 1,2,3-triazole.

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Authors and Affiliations

  1. N. N. Vorozhtsov Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 9 Lavrent’ev Ave., Novosibirsk, 630090, Russia

    A. V. Lipeeva, E. E. Shults, E. A. Makhneva, M. M. Shakirov & G. A. Tolstikov

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  1. A. V. Lipeeva
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  2. E. E. Shults
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  3. E. A. Makhneva
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  4. M. M. Shakirov
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  5. G. A. Tolstikov
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Corresponding author

Correspondence to E. E. Shults.

Additional information

*For Communication 11, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 591-601, April, 2012.

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Lipeeva, A.V., Shults, E.E., Makhneva, E.A. et al. Study of plant coumarins. 12*. Synthesis of 2-(1,2,3-triazolyl)-modified furocoumarins. Chem Heterocycl Comp 49, 551–560 (2013). https://doi.org/10.1007/s10593-013-1281-6

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  • DOI: https://doi.org/10.1007/s10593-013-1281-6

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