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Application of the Recyclization Products of 5-Alkyl(aryl)amino-2-(3-phthalimidopropyl)-1,3-oxazole-4-carbonitriles to the Synthesis of Condensed Tricyclic Nitrogenous Structures

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Chemistry of Heterocyclic Compounds Aims and scope

N-Alkyl(aryl)-3-amino-5H,6H,7H-pyrrolo[1,2-a]imidazole-2-carboxamides were obtained by the interaction of 5-alkyl(aryl)amino-2-(3-phthalimidopropyl)-1,3-oxazole-4-carbonitriles with hydrazine hydrate and have been used for the synthesis of substituted 3H,4H,6H,7H,8H-pyrrolo[2,1-h]purin-4-ones, their thione analogs, and also 1,2,3,6,7,8-hexahydro-4H-pyrrolo[2′,1′:2,3]imidazo[4,5-d]-[1,3,2]diazaphosphinine derivatives.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 1 Murmanska St., Kyiv, 02660, Ukraine

    S. A. Chumachenko, O. V. Shablykin & V. S. Brovarets

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  1. S. A. Chumachenko
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  2. O. V. Shablykin
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  3. V. S. Brovarets
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Correspondence to V. S. Brovarets.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1956–1962, December, 2012.

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Chumachenko, S.A., Shablykin, O.V. & Brovarets, V.S. Application of the Recyclization Products of 5-Alkyl(aryl)amino-2-(3-phthalimidopropyl)-1,3-oxazole-4-carbonitriles to the Synthesis of Condensed Tricyclic Nitrogenous Structures. Chem Heterocycl Comp 48, 1832–1838 (2013). https://doi.org/10.1007/s10593-013-1216-2

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  • DOI: https://doi.org/10.1007/s10593-013-1216-2

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