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N-Aryl-C-nitroazoles. 1. C-nitro-N-phenylazoles (Review)

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Chemistry of Heterocyclic Compounds Aims and scope

Several synthetic approaches to differently substituted nitroazoles and their applications have been described in the literature. Recently, some N-aryl-C-nitroazoles proved to be promising antibacterial and antiprotozoal agents, as well as explosives. However, their synthesis and applications are not well developed. Syntheses of N-aryl-C-nitroazoles are reviewed here for the first time. Part 1 is devoted to synthesis of C-nitro-N-phenylazoles treated in this review as parent compounds. Procedures of selected compounds have been given and their properties verified. Part 2 will contain related information on the derivatives containing additional substituents in one or both aromatic rings. In Part 3, N-aryl group in C-nitroazoles will be replaced by an N-heteroaryl substituent. Nonaromatic compounds and nitroazoles containing a ring heteroatom other than nitrogen will not be included in the review.

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  1. Silesian University of Technology, 4 Krzywoustego St., Gliwice, 44-100, Poland

    M. Kurpet, R. Jędrysiak & J. Suwiński

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  1. M. Kurpet
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1856-1870, December, 2012.

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Kurpet, M., Jędrysiak, R. & Suwiński, J. N-Aryl-C-nitroazoles. 1. C-nitro-N-phenylazoles (Review). Chem Heterocycl Comp 48, 1737–1750 (2013). https://doi.org/10.1007/s10593-013-1205-5

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