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Chemistry of Heterocyclic Compounds

, Volume 48, Issue 11, pp 1628–1633 | Cite as

3-Alkyl-2-phenyl-1-vinylpyrroles from ketoximes and acetylene: an improved synthesis by the Trofimov reaction

  • O. V. Petrova
  • L. N. Sobenina
  • A. I. Mikhaleva
Article

A one-pot synthesis of 3-alkyl-2-phenyl-1-vinylpyrroles, giving high yields at atmospheric pressure, was developed on the basis of reacting alkyl phenyl ketoximes with acetylene in a KOH–DMSO system (the Trofimov reaction).

Keywords

acetylene alkyl phenyl ketoximes 3-alkyl-2-phenyl-1-vinylpyrroles Trofimov reaction 

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • O. V. Petrova
    • 1
  • L. N. Sobenina
    • 1
  • A. I. Mikhaleva
    • 1
  1. 1.A. E. Favorsky Irkutsk Institute of ChemistrySiberian Branch of the Russian Academy of SciencesIrkutskRussia

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