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Chemistry of 3-acyl-2-haloindoles (Review)

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Chemistry of Heterocyclic Compounds Aims and scope

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Methods for the synthesis and transformation of 3-acyl-2-haloindoles, which are polyfunctional reagents used for preparing various indole derivatives, are summarized. The reduction and oxidation of the acyl group, condensation at the carbonyl group, nucleophilic and radical substitution of the halogen atom are considered. Reactions leading to [b]-fused indoles are discussed separately.

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Authors and Affiliations

  1. Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University, 194/2 Stachki Ave., Rostov-on-the-Don, 344090, Russia

    S. V. Den’kina & K. F. Suzdalev

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  1. S. V. Den’kina
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  2. K. F. Suzdalev
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Correspondence to S. V. Den’kina.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1696-1727, November, 2012.

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Den’kina, S.V., Suzdalev, K.F. Chemistry of 3-acyl-2-haloindoles (Review). Chem Heterocycl Comp 48, 1581–1612 (2013). https://doi.org/10.1007/s10593-013-1181-9

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