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Polyfunctional pyrazoles. 7*. Ethyl 1-aryl-4-formylpyrazole-3-carboxylates in the synthesis of 2-aryl-2,4-dihydro-6H-thieno-[3,4-c]pyrazol-6-ones

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Chemistry of Heterocyclic Compounds Aims and scope

A convenient method has been developed for the synthesis of 2,4-dihydro-6H-thieno[3,4-c]pyrazol-6-ones by means of an intramolecular cyclization of 4-sulfanylmethylpyrazole-3-carboxylic acids. The latter were prepared from ethyl 4-formylpyrazole-3-carboxylates via the intermediate 4-hydroxy-methyl-, 4-chloromethyl-, and 4-thioureidomethyl derivatives.

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Authors and Affiliations

  1. Bukovinian State Medical University, 2 Teatralnaya Sq., Chernivtsy, 58000, Ukraine

    M. K. Bratenko & M. M. Barus

  2. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv, 02660, Ukraine

    M. V. Vovk

Authors
  1. M. K. Bratenko
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  2. M. M. Barus
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  3. M. V. Vovk
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Correspondence to M. K. Bratenko.

Additional information

*For Communication 6, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1657-1661, October, 2012.

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Bratenko, M.K., Barus, M.M. & Vovk, M.V. Polyfunctional pyrazoles. 7*. Ethyl 1-aryl-4-formylpyrazole-3-carboxylates in the synthesis of 2-aryl-2,4-dihydro-6H-thieno-[3,4-c]pyrazol-6-ones. Chem Heterocycl Comp 48, 1545–1549 (2013). https://doi.org/10.1007/s10593-013-1171-y

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  • DOI: https://doi.org/10.1007/s10593-013-1171-y

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