Synthesis of 5-[(4-methylphenyl)sulfinyl]-and 5-[(4-methylphenyl)sulfonyl]-1-phenyl-1 H-tetrazoles
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It is known that the reaction of 5-alkylsulfanyltetrazoles with hydrogen peroxide depends on the reaction conditions and can give 5-alkylsulfinyl- or 5-alkylsulfonyltetrazoles [1, 2, 3]. However, the oxidation of 5-arylsulfanyltetrazoles has not previously been studied, probably because of the difficulty in obtaining these compounds. We have earlier proposed a method for preparation of 1-substituted 5-arylsulfanyltetrazoles . In this work we have studied the oxidation of 5-[(4-methylphenyl)sulfanyl]-1-phenyl-1 H-tetrazole (1) by hydrogen peroxide in acetic acid.
Keywords5-arylsulfanyltetrazoles hydrogen peroxide microwave activation oxidation
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