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Regiodirected synthesis of polyfluoro-alkylated pyrimido[1,2-a]benzimidazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Conditions have been found for the regiodirected cyclization of 2-aminobenzimidazoles using ethyl 3-oxo-3-polyfluoroalkyl-2-ethoxymethylidenepropionates at the ethoxymethylidenefluoroacyl fragment to give ethyl pyrimidobenzimidazole-3-carboxylates.

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Authors and Affiliations

  1. I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22/20 S. Kovalevska St., Academic St., Yekaterinburg, 620990, Russia

    M. V. Goryaeva, Ya. V. Burgart, V. I. Saloutin & O. N. Chupakhin

Authors
  1. M. V. Goryaeva
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  2. Ya. V. Burgart
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  3. V. I. Saloutin
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  4. O. N. Chupakhin
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Corresponding author

Correspondence to V. I. Saloutin.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 395-399, February, 2012.

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Goryaeva, M.V., Burgart, Y.V., Saloutin, V.I. et al. Regiodirected synthesis of polyfluoro-alkylated pyrimido[1,2-a]benzimidazoles. Chem Heterocycl Comp 48, 372–376 (2012). https://doi.org/10.1007/s10593-012-1000-8

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  • DOI: https://doi.org/10.1007/s10593-012-1000-8

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