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Ethyl 5-amino-3-oxo-1,2-dihydro-1H-pyrazole-1-carboxylate in the selective synthesis of partially hydrogenated pyrazolo[3,4-b]pyridin-3-ones

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Chemistry of Heterocyclic Compounds Aims and scope

Ethyl 5-amino-3-oxo-1,2-dihydro-1H-pyrazole-1-carboxylate undergoes selective cyclocondensation with 1,3-dicarbonyl compounds or their synthetic equivalents to give ethyl 3-oxo-1,2-dihydro-pyrazolo[3,4-b]pyridine-1-carboxylates which are readily converted to their 1-unsubstituted analogs.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Ukraine National Academy of Sciences, 5 Murmanska St., Kyiv, 02094, Ukraine

    P. S. Lebedˈ, N. G. Mozgovaya, P. O. Kos & M. V. Vovk

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  1. P. S. Lebedˈ
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  2. N. G. Mozgovaya
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  3. P. O. Kos
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  4. M. V. Vovk
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Correspondence to P. S. Lebedˈ.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 390-394, February, 2012.

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Lebedˈ, P.S., Mozgovaya, N.G., Kos, P.O. et al. Ethyl 5-amino-3-oxo-1,2-dihydro-1H-pyrazole-1-carboxylate in the selective synthesis of partially hydrogenated pyrazolo[3,4-b]pyridin-3-ones. Chem Heterocycl Comp 48, 368–371 (2012). https://doi.org/10.1007/s10593-012-0999-x

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  • DOI: https://doi.org/10.1007/s10593-012-0999-x

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