Advertisement

Chemistry of Heterocyclic Compounds

, Volume 48, Issue 2, pp 358–361 | Cite as

Synthesis of 3-{3-[(4-methylcyclohex-3-enyl-carbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid anilides

  • D. ZicaneEmail author
  • I. Ravina
  • Z. Tetere
  • I. Rijkure
Article

With the aim of discovering potential diuretic agents amongst quinazoline anilides we have prepared anilides of 3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid. Optimal conditions for obtaining of the starting acid have been established, and anilides have been synthesized by the mixed anhydrides method.

Keywords

anilides hydrazides mixed anhydrides propionic acid quinazolines succinic anhydride 

References

  1. 1.
    I. V. Ukrainets, V. V. Kravtsova, A. A. Tkach, and G. Sim, Khim. Geterotsikl. Soedin., 233 (2008). [Chem. Heterocycl. Compd., 44, 173 (2008)].Google Scholar
  2. 2.
    I. V. Ukrainets, N. L. Bereznyakova, V. A. Parenikov, and V. N. Kravchenko, Khim. Geterotsikl. Soedin., 78 (2008). [Chem. Heterocycl. Compd., 44, 64 (2008)].Google Scholar
  3. 3.
    D. R. Zicane, I. T. Ravina, I. A. Rijkure, Z. F. Tetere, E. J. Gudriniece, and U. O. Kalejs, Zh. Org. Khim., 36, 521 (2000).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2012

Authors and Affiliations

  1. 1.Riga Technical UniversityRigaLatvia

Personalised recommendations