Chemistry of Heterocyclic Compounds

, Volume 48, Issue 2, pp 358–361 | Cite as

Synthesis of 3-{3-[(4-methylcyclohex-3-enyl-carbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid anilides

  • D. ZicaneEmail author
  • I. Ravina
  • Z. Tetere
  • I. Rijkure

With the aim of discovering potential diuretic agents amongst quinazoline anilides we have prepared anilides of 3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid. Optimal conditions for obtaining of the starting acid have been established, and anilides have been synthesized by the mixed anhydrides method.


anilides hydrazides mixed anhydrides propionic acid quinazolines succinic anhydride 


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Copyright information

© Springer Science+Business Media, Inc. 2012

Authors and Affiliations

  1. 1.Riga Technical UniversityRigaLatvia

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