Copper-catalyzed arylation of tetrazole-5-thiones upon convection heating and microwave activation conditions
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The arylation of 1-phenyltetrazole-5-thione using a series of iodobenzene derivatives in the presence of cuprous chloride and a ligand such as ethylenediamine. It was shown that the use of microwave activation permitted shortening of the reaction time, increasing yields and simplification of the reaction products isolation.
Keywordsaryl iodide cuprous chloride ethylenediamine tetrazole-5-thione arylation microwave activation
- 1.M. A. Gol'tsberg and G. I. Koldobskii, Zh. Org. Khim., 32, 1238 (1996).Google Scholar