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Chemistry of Heterocyclic Compounds

, Volume 48, Issue 2, pp 343–354 | Cite as

Dealkylation of quaternary 1-alkylazolo[a]pyridinium salts

  • L. M. PotikhaEmail author
  • A. R. Turelik
  • A. V. Shelepyuk
  • V. A. Kovtunenko
Article

A convenient method is proposed for the preparation of new derivatives of free heterocyclic bases of imidazo[1,2-a]pyridine, pyrido[1,2-a]benzimidazole, and [1,2,4]triazolo[4,3-a]pyridine series. This method entails the dealkylation of N-(2-cyanoethyl)- or N-benzylazolopyridinium quaternary salts in the presence of bases and reaction with ammonium formate in the presence of Pd/C, respectively.

Keywords

imidazo[1,2-a]pyridine pyrido[1,2-a]benzimidazole [1,2,4]triazolo[4,3-a]pyridine alkylation cyclization dealkylation 

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Copyright information

© Springer Science+Business Media, Inc. 2012

Authors and Affiliations

  • L. M. Potikha
    • 1
    Email author
  • A. R. Turelik
    • 1
  • A. V. Shelepyuk
    • 1
  • V. A. Kovtunenko
    • 1
  1. 1.Taras Shevchenko Kyiv National UniversityKyivUkraine

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