A convenient method is proposed for the preparation of new derivatives of free heterocyclic bases of imidazo[1,2-a]pyridine, pyrido[1,2-a]benzimidazole, and [1,2,4]triazolo[4,3-a]pyridine series. This method entails the dealkylation of N-(2-cyanoethyl)- or N-benzylazolopyridinium quaternary salts in the presence of bases and reaction with ammonium formate in the presence of Pd/C, respectively.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 364-376, February, 2012.
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Potikha, L.M., Turelik, A.R., Shelepyuk, A.V. et al. Dealkylation of quaternary 1-alkylazolo[a]pyridinium salts. Chem Heterocycl Comp 48, 343–354 (2012). https://doi.org/10.1007/s10593-012-0995-1
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DOI: https://doi.org/10.1007/s10593-012-0995-1