First representative of 6b,9-epoxyisoindolo-[2,1-a]quinazoline-10-carboxylic acids
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We have developed a synthetic route for the preparation of epoxyisoindolones condensed with various heterocycles based on the cycloaddition of unsaturated acid derivatives to α-furyl-substituted hydrogenated azaheterocycles . To explore the synthetic scope of this method we have prepared the 3-alkyl-2-furyl- quinazolines 1 by the method reported in  and studied their reaction with maleic anhydride for the first time.
Keywords2-furylquinazolin-4-ones furfurylamines isoindolo[2,1-a]quinazolines Diels-Alder reaction intramolecular [4 + 2] cycloaddition
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