Vinylation of pyridylcarboxamides with vinyltrimethoxysilane
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A convenient method has been developed for the direct N-vinylation of pyridylcarboxamides with vinyltrimethoxysilane in the presence of copper(II) acetate and tetrabutylammonium fluoride. The yield of N-vinylamides depends on the nature of the starting amide and the solvent. The molecular structure of the products was confirmed by X-ray structural analysis.
Keywordsamide copper(II) acetate vinyl amide vinyltrimethoxysilane silane catalysis X-ray structural analysis
The work was carried out with the assistance of the European Social Fund (ESF No. 2009/0197/1DP/126.96.36.199.0/09/APIA/VIAA/014), and also a grant from the Latvian Council of Science (No. 09.1588).