The synthesis of 2-(N-R-amino)- and 2-(N-vinylcarbonylamino)acylbenzenes has been carried out and their heterocyclization into quinolin-2-ones under the action of sodium ethylate has been studied.
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The work was carried out with the financial support of a grant "Academician N. S. Zefirov Leading Scientific School".
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1345–1363, September, 2011.
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Mochalov, S.S., Chasanov, M.I., Fedotov, A.N. et al. Synthesis of quinolin-2-ones by an intramolecular Knoevenagel condensation and by tandem Michael–Knoevenagel heterocyclization. Chem Heterocycl Comp 47, 1105–1121 (2011). https://doi.org/10.1007/s10593-011-0881-2
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DOI: https://doi.org/10.1007/s10593-011-0881-2