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Synthesis of quinolin-2-ones by an intramolecular Knoevenagel condensation and by tandem Michael–Knoevenagel heterocyclization

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Chemistry of Heterocyclic Compounds Aims and scope

The synthesis of 2-(N-R-amino)- and 2-(N-vinylcarbonylamino)acylbenzenes has been carried out and their heterocyclization into quinolin-2-ones under the action of sodium ethylate has been studied.

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The work was carried out with the financial support of a grant "Academician N. S. Zefirov Leading Scientific School".

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State University, 1, bld. 3 Leninskie gory, Moscow, 119992, Russia

    S. S. Mochalov, M. I. Chasanov, A. N. Fedotov & N. S. Zefirov

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  1. S. S. Mochalov
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  2. M. I. Chasanov
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  3. A. N. Fedotov
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  4. N. S. Zefirov
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Correspondence to S. S. Mochalov.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1345–1363, September, 2011.

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Mochalov, S.S., Chasanov, M.I., Fedotov, A.N. et al. Synthesis of quinolin-2-ones by an intramolecular Knoevenagel condensation and by tandem Michael–Knoevenagel heterocyclization. Chem Heterocycl Comp 47, 1105–1121 (2011). https://doi.org/10.1007/s10593-011-0881-2

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  • DOI: https://doi.org/10.1007/s10593-011-0881-2

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