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4-hydroxy-2-quinolones. 200*. Bromination of 1-R-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid pyridinylmethylene hydrazides

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Chemistry of Heterocyclic Compounds Aims and scope

The behavior of 1-R-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid pyridinylmethylene- hydrazides under bromination conditions using molecular bromine has been studied. It has been found that the 1-N-allyl derivative is characteristically halocyclized to the corresponding oxazolo[3,2-a]-quinoline, whereas the 1-N-hexyl-substituted acylhydrazone is unexpectedly brominated in the azomethine fragment.

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Authors and Affiliations

  1. National University of Pharmacy, 53 Pushkinska St., Kharkiv, 61002, Ukraine

    I. V. Ukrainets

  2. Institute of Chemical Technologies, V. Dalˈ Eastern-Ukrainian National University, 31 Lenin St., Rubizhne, 93003, Luhansk Region, Ukraine

    E. V. Mospanova & O. V. Gorokhova

  3. Institute for Single Crystals, National Academy of Sciences of Ukraine, 60 Lenin St., Kharkiv, 61001, Ukraine

    S. V. Shishkina

Authors
  1. I. V. Ukrainets
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  2. E. V. Mospanova
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  3. O. V. Gorokhova
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  4. S. V. Shishkina
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Corresponding author

Correspondence to I. V. Ukrainets.

Additional information

*For Communication 199, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1232–1237, August, 2011.

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Ukrainets, I.V., Mospanova, E.V., Gorokhova, O.V. et al. 4-hydroxy-2-quinolones. 200*. Bromination of 1-R-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid pyridinylmethylene hydrazides. Chem Heterocycl Comp 47, 1014–1019 (2011). https://doi.org/10.1007/s10593-011-0868-z

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  • DOI: https://doi.org/10.1007/s10593-011-0868-z

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