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Chemistry of Heterocyclic Compounds

, Volume 47, Issue 7, pp 851–855 | Cite as

Cerium(IV) ammonium nitrate catalyzed green synthesis of 2-substituted 2,3-dihydro- quinazolin-4(1H)-ones using a grinding technique

  • M. WangEmail author
  • J. J. Gao
  • Z. G. Song
  • L. Wang
Article

An efficient and facile method for the synthesis of 2-substituted 2,3-dihydro-quinazolin-4(1H)-ones from anthranilamide with aldehydes or ketones in the presence of cerium(IV) ammonium nitrate in water by a grinding technique has been developed. The structures of the new products were proved by IR, 1H NMR, MS, and elemental analysis. A plausible mechanism for the formation of these products is proposed.

Keywords

anthranilamide cerium(IV) ammonium nitrate 2,3-dihydroquinazolin-4(1H)-one grinding technique 

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Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  1. 1.College of Chemistry, Chemical Engineering and Food SafetyBohai UniversityJinzhouP. R. China
  2. 2.Center for Science & Technology ExperimentBohai UniversityJinzhouP. R. China

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