One-pot triple-component reaction of 4-hydroxycoumarin with aromatic aldehydes and 2-aminobenzimidazole, 3-amino-1H-1,2,4-triazole, or 6-aminouracil in acetonitrile in the presence of catalytic amounts of sulfamic acid led to a chemoselective synthesis of chromeno[4,3-d]pyrimidine-6-one, triazolo[1,5-a]pyrimidin-5-one, and pyrido[2,3-d]-pyrimidine-2,4,7-trione derivatives, respectively, in good yields.
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We gratefully acknowledge partial financial support from the Alzahra University Research Council.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 892–900, June, 2011.
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Heravi, M.M., Saeedi, M., Beheshtiha, Y.S. et al. One-pot chemoselective synthesis of novel fused pyrimidine derivatives. Chem Heterocycl Comp 47, 737–744 (2011). https://doi.org/10.1007/s10593-011-0828-7
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DOI: https://doi.org/10.1007/s10593-011-0828-7