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Substituted 2-aminonicotinamides in the synthesis of pyrido[2,3-d]pyrimidin-4(1H)-ones, 2,3-dihydropyrido- [2,3-d]pyrimidin-4(1H)-ones, and 11b,12-dihydropyrido- [2',3':4,5]pyrimido[2,1-a]isoindole-5,7-diones

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Chemistry of Heterocyclic Compounds Aims and scope

The reactions of 2-aminonicotinamides with triethyl orthoformate, carboxylic acids chlorides, aldehydes, and 2-formylbenzoic acid were studied. As a result pyrido[2,3-d]pyrimidin-4(1H)-ones, 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones, and 5,7,11b,12-tetrahydropyrido[2',3':4,5]pyrimido- [2,1-a]isoindole-5,7-diones were obtained.

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References

  1. W. P. Purcell, R. D. Gilliom, and H. A. Parish, US Patent 4361700; Chem. Abstr., 98, 89387 (1983).

    Google Scholar 

  2. M. Mohsen, J. Serb. Chem. Soc., 56, 383 (1991); Ref. Zh. Khim., 4zh291 (1992).

    Google Scholar 

  3. A. Monge, V. Martinez-Merino, M. A. Simon, and C. Sanmartin, J. Heterocycl. Chem., 29, 1545 (1992).

    Article  CAS  Google Scholar 

  4. H. A. Parish, R. D. Gilliom, W. P. Purcell, R. K. Browne, R. F. Spirk, and H. D. White, J. Med. Chem., 25, 98 (1982).

    Article  CAS  Google Scholar 

  5. V. D. Strelkov, in: Proceedings of the International Technological Conference "Biological Plant Protection, a Basis for Stabilizing Agroecosystems" [in Russian], Krasnodar (2004), p. 393.

  6. V. P. Litvinov, L. A. Rodinovskaya, Yu. A. Sharanin, and A. M. Shestopalov, Sulfur Rep., 13, 1 (1992).

    Article  CAS  Google Scholar 

  7. N. I. Shram and M. E. Konshin, Khim. Geterotsikl. Soedin., 114 (1985). [Chem. Heterocycl. Comp., 21, 93 (1985)].

    Google Scholar 

  8. L. M. Demina and M. E. Konshin, Khim. Geterotsikl. Soedin., 1234 (1992). [Chem. Heterocycl. Comp., 28, 1046 (1992)].

    Google Scholar 

  9. I. S. Arustamova and V. T. Piven', Khim. Geterotsikl. Soedin., 61 (1999). [Chem. Heterocycl. Comp., 35, 58 (1999)].

    Google Scholar 

  10. R. Kwork, J. Heterocycl. Chem., 15, 877 (1978).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Kuban State Agrarian University, 13 Kalinina St., Krasnodar, 350044, Russia

    E. A. Sidorova, E. S. Kostenko, I. S. Arustamova & E. A. Kaigorodova

  2. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Prospect, Moscow, 119991, Russia

    L. D. Konyushkin

Authors
  1. E. A. Sidorova
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  2. E. S. Kostenko
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  3. I. S. Arustamova
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  4. E. A. Kaigorodova
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  5. L. D. Konyushkin
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Correspondence to L. D. Konyushkin.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 362–370, March, 2011.

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Sidorova, E.A., Kostenko, E.S., Arustamova, I.S. et al. Substituted 2-aminonicotinamides in the synthesis of pyrido[2,3-d]pyrimidin-4(1H)-ones, 2,3-dihydropyrido- [2,3-d]pyrimidin-4(1H)-ones, and 11b,12-dihydropyrido- [2',3':4,5]pyrimido[2,1-a]isoindole-5,7-diones. Chem Heterocycl Comp 47, 294–301 (2011). https://doi.org/10.1007/s10593-011-0756-6

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  • DOI: https://doi.org/10.1007/s10593-011-0756-6

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