Benzazoles. 4. Synthesis and chemical reactions of 6-chlorosulfonylbenzoxazolin-2-ones

  • M. E. Karimova
  • D. A. Dushamov
  • R. Sh. Kuryazov
  • N. S. MukhamedovEmail author

The corresponding 6-chlorosulfonyl derivatives were synthesized from benzoxazolin-2-one and its 3-methyl derivative by treatment with chlorosulfonic acid. By treatment of the compounds obtained with water and other nucleophilic reagents (aliphatic and heterocyclic amines) 2-oxobenzoxazoline-6-sulfonic acids and a series of their amides were obtained, while reduction with SnCl2·2H2O gave 6-mercaptobenzoxazolin-2-ones.


amides of 2-oxobenzoxazoline-6-sulfonic acids 6-mercaptobenzoxazolin-2-ones 6-chloro-sulfonylbenzoxazolin-2-ones reduction nucleophilic substitution electrophilic substitution 


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Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • M. E. Karimova
    • 1
  • D. A. Dushamov
    • 1
    • 2
  • R. Sh. Kuryazov
    • 3
  • N. S. Mukhamedov
    • 3
    Email author
  1. 1.Khorezm Mamun AcademyKhorezm RegionRepublic of Uzbekistan
  2. 2.Al-Khorezm Urgench State UniversityUrgenchRepublic of Uzbekistan
  3. 3.Acad. S. Yunusov Institute of Chemistry of Plant SubstancesAcademy of Sciences of the Republic UzbekistanTashkentRepublic of Uzbekistan

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