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Chemistry of Heterocyclic Compounds

, Volume 47, Issue 1, pp 36–44 | Cite as

Novel structural analogs of glyphosate based on azoles. 1. Synthesis of 1H-imidazoles containing carboxyl and phosphoryl groups in the ring

  • N. V. Pavlenko
  • T. I. Oos
  • Yu. L. YagupolskiiEmail author
  • A. van Almsick
  • L. Willms
Article

A general method has been developed for the synthesis of 1H-imidazoles containing a phosphoryl group in positions 2 or 4(5) based on lithium intermediates. The possibility of further functionalization of the ring using electrophiles has also been demonstrated.

Keywords

imidazole lithium intermediates electrophiles hydrolysis protecting groups phosphorylation 

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Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • N. V. Pavlenko
    • 1
  • T. I. Oos
    • 1
  • Yu. L. Yagupolskii
    • 1
    Email author
  • A. van Almsick
    • 2
  • L. Willms
    • 2
  1. 1.Institute of Organic ChemistryNational Academy of Sciences of UkraineKyivUkraine
  2. 2.Bayer CropScience GmbHFrankfurt am MainGermany

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