Opening of the furan ring in 2-R-amino- 3-furfurylthiophenes by the action of acids

  • T. A. StroganovaEmail author
  • V. K. Vasilin
  • E. A. Elizarova

A new method is proposed for the production of derivatives of thieno[2,3-b]pyrrole on the basis of acid-catalyzed recyclization of the furan ring in 2-R-amino-3-furfurylthiophenes. It was established that the direction of the transformations occurring under the influence of a mixture of hydrochloric and acetic acids and also the structure of the obtained compounds depend on the nature of the protecting group.


2-amino-3-benzoylthiophenes 2-R-amino-3-furfurylthiophenes thieno[2,3-b]pyrrole furan ring opening recyclization 


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Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • T. A. Stroganova
    • 1
    Email author
  • V. K. Vasilin
    • 1
  • E. A. Elizarova
    • 1
  1. 1.Kuban State University of Technology, Department of Organic ChemistryKrasnodarRussia

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