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Synthesis and tautomerism of 2-(3,5-diaryl-1H-pyrazol-4-yl)-1-methyl-1H-benzimidazoles

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Chemistry of Heterocyclic Compounds Aims and scope

The cyclocondensation of 1-methyl-2-phenacyl-1H-benzimidazole with aroylhydrazines yields 2-(3,5-diaryl-1H-pyrazol-4-yl)-1-methyl-1H-benzimidazoles. The 1H NMR spectra indicate that these products display tautomerism. The more stable tautomers have structures containing electron-donor aryl substituents at C-5 and electron-withdrawing aryl substituents at C-3 of the pyrazole ring.

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Authors and Affiliations

  1. Institute of Organic Chemistry, National Academy of Sciences, Kiev, 02094, Ukraine

    I. B. Dzvinchuk & M. O. Lozinskii

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  1. I. B. Dzvinchuk
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  2. M. O. Lozinskii
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Correspondence to I. B. Dzvinchuk.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1800–1805, December, 2010.

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Dzvinchuk, I.B., Lozinskii, M.O. Synthesis and tautomerism of 2-(3,5-diaryl-1H-pyrazol-4-yl)-1-methyl-1H-benzimidazoles. Chem Heterocycl Comp 46, 1454–1458 (2011). https://doi.org/10.1007/s10593-011-0691-6

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  • DOI: https://doi.org/10.1007/s10593-011-0691-6

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