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Mechanism of formation of 3-methyl derivatives of imidazo[2,1-b]thiazoles and their benzo analogs in the reactions of 2-mercaptoimidazole and 2-mercaptobenzimidazole with 1,3-dichloroacetone under phase-transfer catalysis conditions

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Chemistry of Heterocyclic Compounds Aims and scope

The mechanism of the unexpected formation of 3-methyl derivatives of imidazo[2,1-b]thiazoles in the system 2-mercaptoimidazole–1,3-dichloroacetone–solid K2CO3–solid KI–18-crown-6–toluene has been studied. The structure of 3-methyl[1,3]thiazolo[3,2-a]benzimidazole has been confirmed using X-ray structural analysis.

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Correspondence to E. Abele.

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E. Lukevics (Deceased).

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1725–1729, November, 2010.

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Beresneva, T., Belyakov, S., Abele, E. et al. Mechanism of formation of 3-methyl derivatives of imidazo[2,1-b]thiazoles and their benzo analogs in the reactions of 2-mercaptoimidazole and 2-mercaptobenzimidazole with 1,3-dichloroacetone under phase-transfer catalysis conditions. Chem Heterocycl Comp 46, 1400–1404 (2011). https://doi.org/10.1007/s10593-011-0678-3

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  • DOI: https://doi.org/10.1007/s10593-011-0678-3

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