Epoxidation of 4-alkylidene(arylidene)-1-phenyl-3,5-pyrazolidinediones using alkaline hydrogen peroxide gave the corresponding 5-phenyl-1-oxa-5,6-diazaspiro[2.4]heptane-4,7-dione derivatives. Their reaction with nucleophilic reagents was investigated. The resulting products depend on the type of the diazaspiro compound and/or the nucleophile used.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1659–1669, November, 2010.
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Metwally, S.A.M., Mohamed, T.A., Moustafa, O.S. et al. Novel synthesis of highly functionalized pyrazolone systems via rearrangement of 5-phenyl-1-oxa-5,6-diazaspiro[2.4]heptane-4,7-diones. Chem Heterocycl Comp 46, 1344–1353 (2011). https://doi.org/10.1007/s10593-011-0671-x
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DOI: https://doi.org/10.1007/s10593-011-0671-x