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Chemistry of Heterocyclic Compounds

, Volume 46, Issue 7, pp 879–886 | Cite as

Rapid acid hydrolysis of 5-aryl-3-(β-thiomorpholinoethyl)-1,2,4-oxadiazoles

  • L. A. KayukovaEmail author
  • M. A. Orazbaeva
  • G. I. Gapparova
  • K. M. Beketov
  • A. A. Espenbetov
  • M. F. Faskhutdinov
  • B. T. Tashkhodjaev
Article

The acid hydrolysis of a series of 5-aryl-3-(β-thiomorpholinoethyl)-1,2,4-oxadiazoles gave substituted benzoic acids and 2-amino-8-thia-1-aza-5-azoniaspiro[4.5]dec-1-ene chloride hydrate, whose structure was demonstrated by spectral methods and X-ray diffraction structural analysis.

Keywords

5-aryl-3-(β-thiomorpholinoethyl)-1,2,4-oxadiazoles 2-amino-8-thia-1-aza-5-azoniaspiro-[4.5]dec-1-ene chloride hydrate substituted benzoic acids acid hydrolysis X-ray diffraction structural analysis. 

References

  1. 1.
    K. M. Beketov, J. T. Welch, P. J. Toscano, L. A. Kayukova, A. L. Akhelova, and K. D. Praliev, Zh. Strukt. Khim., 45, 540 (2004).Google Scholar
  2. 2.
    L. A. Kayukova, K. D. Praliev, and I. S. Zhumadil'daeva, Khim. Geterotsikl. Soed., 253 (2003). [Chem. Heterocycl. Comp., 39, 223 (2003)].Google Scholar
  3. 3.
    L. A. Kayukova, K. M. Beketov, A. L. Akhelova, and K. D. Praliev, Khim. Geterotsikl. Soedin., 1057 (2006). [Chem. Heterocycl. Comp., 42, 914 (2006)].Google Scholar
  4. 4.
    L. A. Kayukova and M. A. Orazbaeva, Izv. Ministerstv. Obraz. Nauki Resp. Kazakhstan, Nats. Akad. Nauk Resp. Kazakhstan, Ser. Khim., No. 5, 37 (2007).Google Scholar
  5. 5.
    L. A. Kayukova and M. A. Orazbaeva, Khim. Zh. Kazakhstan, No. 1, 99 (2008).Google Scholar
  6. 6.
    A. Gordon and R. Ford, The Chemist's Companion, Wiley, New York, London, Sidney, Toronto (1972).Google Scholar
  7. 7.
    G. M. Sheldrick, SHELXS97 and SHELXL97, Univ. Göttingen, Göttingen, Germany (1997).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  • L. A. Kayukova
    • 1
    Email author
  • M. A. Orazbaeva
    • 1
  • G. I. Gapparova
    • 1
  • K. M. Beketov
    • 1
  • A. A. Espenbetov
    • 1
  • M. F. Faskhutdinov
    • 1
  • B. T. Tashkhodjaev
    • 2
  1. 1.A. B. Bekturov Institute of Chemical SciencesAlmatyRepublic of Kazakhstan
  2. 2.S. Yu. Yunusov Institute of the Chemistry of Plant SubstancesAcademy of Sciences of the Republic of UzbekistanTashkentRepublic of Uzbekistan

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