Advertisement

Chemistry of Heterocyclic Compounds

, Volume 46, Issue 7, pp 856–858 | Cite as

Three-component synthesis of 6-aryl-4-methyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-(N-aryl)carboxamides

  • V. L. GeinEmail author
  • T. M. Zamaraeva
  • A. A. Kurbatova
  • M. I. Vakhrin
Article

A three-component synthesis using acetoacetanilides and a mixture of an aromatic aldehyde and urea yields 6-aryl-4-methyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-(N-aryl)carboxamides.

Keywords

N-arylamides 6-aryl-4-methyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-(N-aryl)carboxamides urea three-component synthesis 

References

  1. 1.
    S. O. Kappe, J. Org. Chem., 62, 7201 (1997).CrossRefGoogle Scholar
  2. 2.
    S. O. Kappe, Heterocycles, 45, 1976 (1997).Google Scholar
  3. 3.
    O. V. Fedorova, M. S. Zhidovinova, G. L. Rusinov, and I. G. Ovchinnikova, Izv. Akad. Nauk, Ser. Khim., 2389 (2003).Google Scholar
  4. 4.
    S. V. Vdovina, L. V. Mustakimova, and V. A. Mamedov, Zh. Org. Khim., 44, 638 (2008).Google Scholar
  5. 5.
    V. L. Gein, T. M. Zamaraeva, A. A. Zorina, and M. I. Vakhrin, Zh. Org. Khim., 45, 1591 (2009).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  • V. L. Gein
    • 1
    Email author
  • T. M. Zamaraeva
    • 1
  • A. A. Kurbatova
    • 1
  • M. I. Vakhrin
    • 1
  1. 1.Perm State Pharmaceutical AcademyPermRussia

Personalised recommendations