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2-Aroylhexanones in the synthesis of azoles

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Chemistry of Heterocyclic Compounds Aims and scope

2-Aroylcyclohexanones, obtained from piperidinocyclohexene, react with hydrazine, hydroxylamine, and o-phenylenediamine to give the corresponding derivatives of bicyclic heterocycles – indazole, 2,1-benzisoxazole, and 2-spiro-cyclohexylbenzimidazole. The structure of a derivative of benzyloxazole has been determined by X-ray crystallography.

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Notes

  1. * Here and below the values of the peaks are cited as m/z (I rel).

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Authors and Affiliations

  1. Perm State Pharmaceutical Academy, Perm, 614990, Russia

    A. G. Mikhailovskii, N. G. Bazina, A. A. Pantyukhin & M. I. Vakhrin

  2. Institute of the Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, 142432, Moscow Region, Russia

    Z. G. Aliev & N. G. Bazina

Authors
  1. A. G. Mikhailovskii
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  2. Z. G. Aliev
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  3. N. G. Bazina
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  4. A. A. Pantyukhin
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  5. M. I. Vakhrin
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Corresponding author

Correspondence to A. G. Mikhailovskii.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, 905-911, June 2010.

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Mikhailovskii, A.G., Aliev, Z.G., Bazina, N.G. et al. 2-Aroylhexanones in the synthesis of azoles. Chem Heterocycl Comp 46, 730–735 (2010). https://doi.org/10.1007/s10593-010-0576-0

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  • DOI: https://doi.org/10.1007/s10593-010-0576-0

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