A one-reactor method has been developed for the synthesis of 3-methyl-6-R-6H-thiazolo[4,3-b]-1,2,4-triazolo[4,3-d]-1,3,4-thiadiazoles by the condensation of aromatic aldehydes, thioglycolic acid, and 4-amino-5-methyl-1,2,4-triazole-3(2H)-thione in a sulfuric acid medium.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 761-763, May, 2010.
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Kukaniev, M.A., Akbarova, M.M., Sangov, Z.G. et al. Synthesis of 3-methyl-6-r-6h-thiazolo-[4,3-b]-1,2,4-triazolo[4,3-d]-1,3,4-thiadiazoles. Chem Heterocycl Comp 46, 605–607 (2010). https://doi.org/10.1007/s10593-010-0552-8
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DOI: https://doi.org/10.1007/s10593-010-0552-8