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5-amino-3,4-dihydro-2h-1,2,4-triazole-3-thiones. synthesis and chemosensor properties

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Chemistry of Heterocyclic Compounds Aims and scope

The reaction of 4-arylalkyl- and 4-arylthiosemicarbazides with aroyl isothiocyanates gave substituted 1,2-bis(thiocarbamoyl)hydrazines, which readily cyclize to give previously unreported 4-aroyl 5-arylalkyl- and 4-aroyl-5-arylamino-2H-1,2,4-triazole-3-thiones, respectively. A spectral study of 9-anthrylmethylthiosemicarbazides and derived dihydrotriazolethione indicated the chemosensor activity of these compounds relative to a cation series.

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Authors and Affiliations

  1. Institute of Physical and Organic Chemistry, Southern Federal University, Rostov-on-the-Don, 344090, Russia

    I. E. Tolpygin, G. S. Borodkin, V. A. Bren’ & V. I. Minkin

  2. Southern Scientific Center, Russian Academy of Sciences, Rostov-on-the-Don, 344090, Russia

    E. N. Shepelenko, A. D. Dubonosov, V. A. Bren’ & V. I. Minkin

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  1. I. E. Tolpygin
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  2. E. N. Shepelenko
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  3. G. S. Borodkin
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  4. A. D. Dubonosov
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  5. V. A. Bren’
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  6. V. I. Minkin
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Corresponding author

Correspondence to I. E. Tolpygin.

Additional information

For Communications 18-21, see [1–4].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 686-691, May, 2010.

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Tolpygin, I.E., Shepelenko, E.N., Borodkin, G.S. et al. 5-amino-3,4-dihydro-2h-1,2,4-triazole-3-thiones. synthesis and chemosensor properties. Chem Heterocycl Comp 46, 542–546 (2010). https://doi.org/10.1007/s10593-010-0543-9

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  • DOI: https://doi.org/10.1007/s10593-010-0543-9

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