Chemistry of Heterocyclic Compounds

, Volume 46, Issue 3, pp 342–346 | Cite as

Synthesis of bicyclic pyrimido[2,1-b][1, 3]thiazines based on 3,4-dihydropyrimidine-(1H)-2-thiones

  • I. V. Kulakov
  • D. M. Turdybekov

Bicyclic pyrimido[2,1-b][1, 3]thiazines were produced by the acylation of 4-aryl-substituted 3,4-di-hydropyrimidine(1H)-2-thiones with 3-bromopropionyl chloride, and their structures were proved by the data from X-ray crystallographic analysis.


3,4-dihydropyrimidine(1H)-2-thiones pyrimidino[2,1-b][1, 3]thiazines 3-bromopropionyl chloride intramolecular heterocyclization X-ray crystallographic analysis 


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© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  1. 1.Institute of Organic Synthesis and Coal Chemistry of the Republic of KazakhstanKaragandaRepublic of Kazakhstan
  2. 2.Scientific-Production Holding “Phytochemistry”KaragandaRepublic of Kazakhstan

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